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novembre 2011

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Cerebral tryptophan metabolism in humans in relation to malignant pain.

The authors investigated the cerebral metabolism of tryptophan in patients suffering from malignant pain by means of CSF dosage of tryptophan (Trp), 5-hydroxytryptophan (5-HTP), serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA).

The level of 5-HIAA in patients with pain was 66.48 +/- 13.67 ng/ml, while in those without pain was 25.05 +/- 13.25 ng/ml; the difference was statistically significant, p = 0.001. Leggi tutto...

Autori: 
Ceccherelli F, Costa C, Ischia S, Ischia A, Giron G, Allegri G.
Pubblicato su: 
Funct Neurol. 1989 Oct-Dec;4(4):341-53.

Diode laser in cervical myofascial pain: a double-blind study versus placebo.

We present a double-blind trial in which a pulsed infrared beam was compared with a placebo in the treatment of myofascial pain in the cervical region.

The patients were submitted to 12 sessions on alternate days to a total energy dose of 5 J each. At each session, the four most painful muscular trigger points and five bilateral homometameric acupuncture points were irradiated.

Those in the placebo group submitted to the same number of sessions following an identical procedure, the only difference being that the laser apparatus was nonoperational. Leggi tutto...

Autori: 
Ceccherelli F, Altafini L, Lo Castro G, Avila A, Ambrosio F, Giron GP.
Pubblicato su: 
Clin J Pain. 1989 Dec;5(4):301-4.
File lavoro per esteso: 
application/pdf iconDiode.pdf

[3H] imipramine binding sites are decreased in platelets of chronic pain patients.

Tritiated imipramine binding to whole platelets was measured in sixteen chronic pain patients not suffering from major depression and in a control group.

Maximum binding was significantly lower in chronic pain patients than in the control group, whereas the binding affinity was not significantly different.
 

Autori: 
Magni G, Andreoli F, Arduino C, Arsie D, Ceccherelli F, Ambrosio F, Eandi M.
Pubblicato su: 
Acta Psychiatr Scand. 1987 Jan;75(1):108-10.

Proposed method for double-blind study of reflexotherapy phenomena.(article in italian)

The Authors report their experience with the placebo, an essential step in the clinical study of reflexotherapy.

They assert that also in this branch of medicine it is possible to carry out a "double blind" clinical experimentation by means of placebo, that is, an essential condition in order to develop a scientific assessment of both the limits and the potentialities of reflexotherapy.
 

Autori: 
Ceccherelli F, Ambrosio F, Manani G, Zanardi L, Giusti P.
Pubblicato su: 
Minerva Med. 1980 Mar 31;71(12):919-22.
File lavoro per esteso: 
application/pdf icondoppiocieco.pdf

Therapy of primary headache with somatic acupuncture. Proposal for an experimental protocol for a multicenter study.(article in italian)

In questo lavo gli Autori propongono uno schema per una ricerca policentrica sul trattamento delle cefalee primarie mediante agopuntura.

In esso vengono riportate delle note classificative delle algie del capo, elementi per l’inquadramemo nosologico delle varie forme e cenni di diagnosi differenziale fra di esse. Leggi tutto...

Autori: 
Ceccherelli F, Ambrosio F, Vettorazzi M, Sorbara C, Caracausi R, Roccia L.
Pubblicato su: 
Minerva Med. 1982 Mar 31;73(13):731-53.
File lavoro per esteso: 
application/pdf iconcefalee.pdf

Comparison study between acupuncture and pentazocine analgesic and respiratory post-operative effects.

The authors studied the effects of acupuncture and pentazocine on post-operative respiratory function and pain management on patients hysterectomized by means of a subumbilical midline incision.

The acupunctural technique consisted of GB-26, St-36, Sp-6 and auricular Shen-Men bilateral electrostimulation for 40 minutes. Leggi tutto...

Autori: 
Facco E, Manani G, Angel A, Vincenti E, Tambuscio B, Ceccherelli F, Troletti G, Ambrosio F, Giron GP.
Pubblicato su: 
Am J Chin Med. 1981 Autumn;9(3):225-35.

The influence of acupuncture on blood serum levels of tryptophan in healthy volunteers subjected to ketamine anesthesia.

Ketamine, 2-(0-chlorophenyl)-2-(methylamino)-cyclohexanone, is a general anesthetic which on awakening produces psychic disturbance correlated with the metabolism of serotonin.

Since it is know that acupuncture increases cerebral serotonin, the blood levels of total and free tryptophan, its precursor, were studied in healthy volunteers to find out if the anti-hallucinatory action of acupuncture is dependent on an increase in cerebral serotonin.

Autori: 
Costa C, Ceccherelli F, Ambrosio F, Baron P, De Antoni A, Vanzan S, Allegri G, Manani G.
Pubblicato su: 
Acupunct Electrother Res. 1982;7(2-3):123-32.

Influence of acupuncture on the postoperative complications following ketamine anesthesia. The importance of manual stimulation of point R and shen menn.

The Authors have investigated the antihallucinogenic and sedative effects of auricular points R and shen menn during surgery under ketamine anesthesia.

The results demonstrate that the insertion of the needle in point R is very efficient in reducing hallucinations of ketamine emergence, while the insertion of needle in auricular point shen menn causes only a brief period of sedation in the beginning of the emergence period.

The acupunctural technique employed by the Authors has been shown to increase considerably approbation of ketamine anesthesia.
 

Autori: 
Ceccherelli F, Manani G, Ambrosio F, Angel A, Valenti S, Facco E, Giron GP.
Pubblicato su: 
Acupunct Electrother Res. 1981;6(4):255-64.

TRATTAMENTO AGOPUNTURALE DI UN DOPPIO ARTO FANTASMA DOLOROSO.

M.B. di 78 anni, diabetico insulino-dipendente, vasculopatico importante, ha subito l’amputazione di ambedue gli arti inferiori per insufficienza vascolare nel 2003 dopo aver sofferto per anni il dolore alle gambe.
Il dolore è continuo, è massimo alla notte e tiene sveglio il paziente che si addormenta verso mattina.  Il paziente assumeva: Pregabalin 3 cp da 75 mg e Contramal 20 gh al bisogno. L’intensità del dolore misurata con la VAS è stata di 84. Il paziente ha avuto difficoltà a compilare il Mc Gill Pain Questionnaire. Leggi tutto...

DISFAGIA E XEROSTOMIA IN ESITI DI K DEL PAVIMENTO ORALE

Paziente maschio di 61 anni operato nel 1999 di “CARCINOMA SQUAMOSO DEL SOLCO AMIGDALOGLOSSO SX CON METASTASI LATERO-CERVICALE” con il seguente intervento: Svuotamento radicale linfonodale latero-cervicale, sottomandibolare e sottomentoniero sx con emipelviglossectomia ed emifaringectomia sx con ricostruzione con lembo ad isola muscolo-cutanea e tracheotomia.

Ha quindi subito un ciclo di radioterapia che gli ha provocato un ricovero per: odinofagia in grave mucosità del cavo orale – radiotermite in esiti di radioterapia. Leggi tutto...