The Authors have explored a new complementary approach, employed in the last 40 years for, among other uses, medical purposes: oxygen-ozone therapy. Anecdotal works have highlighted interesting results obtained in disk herniation with infiltration of paravertebral muscles with oxygen-ozone.

To verify the existence of a nociceptive effect and investigate a possible mechanism of action, an experimental model of edema induction by subcutaneous capsaicin injection in the rat paw was employed. Leggi tutto...

The modality of needle stimulation in acupuncture is part of the concept of the ìintensityî of the stimulation, a variable indicating the ìdosageî of the treatment administered.

In this study we intend to compare the effect of superficial and deep needle insertion in the leg ipsilateral or contralateral to the paw treated with capsaicin. Leggi tutto...

Neurogenic inflammation, includes vasodilation, the increase of vasal permeability and edema due to the release of neuromediators from nerve endings.

A modulation of the release of neurotransmitters, from nerve endings and neurogenic inflammation related phenomena, was observed with the administration of drugs or of neurotransmitters inhibiting the release of neuropeptides from capsaicin-sensible neurons, among which morphine and other endogenous agonist opioids seem to be effective. Leggi tutto...