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Modifications of [3H]imipramine binding sites in platelets of chronic pain patients treated with mianserin.

Tritiated imipramine binding to whole platelets was measured in 16 chronic pain patients who were free from major depression, and in a control group.

The maximum binding was significantly lower in chronic pain patients than in the control group, whereas the binding affinity was not significantly different.

Twelve patients were treated with mianserin for 21 days; this produced a significant improvement in the mean scores for pain (evaluated with the McGill Questionnaire) and depressive symptoms (assessed with the Zung Self-Rating Scale). Leggi tutto...

Autori: 
Magni G, Andreoli F, Arduino C, Arsie D, Ceccherelli F, Ambrosio F, Dodi G, Eandi M.
Pubblicato su: 
Pain. 1987 Sep;30(3):311-20.

Proposed method for double-blind study of reflexotherapy phenomena.(article in italian)

The Authors report their experience with the placebo, an essential step in the clinical study of reflexotherapy.

They assert that also in this branch of medicine it is possible to carry out a "double blind" clinical experimentation by means of placebo, that is, an essential condition in order to develop a scientific assessment of both the limits and the potentialities of reflexotherapy.
 

Autori: 
Ceccherelli F, Ambrosio F, Manani G, Zanardi L, Giusti P.
Pubblicato su: 
Minerva Med. 1980 Mar 31;71(12):919-22.
File lavoro per esteso: 
application/pdf icondoppiocieco.pdf
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